The term heart sound refers to the noise generated by the heart during its normal functioning. Its antonyms can be classified into two groups, physiological and pathological. Physiological antonyms include silence, quietness, stillness, and hush, indicating the absence of heart sounds. On the other hand, pathological antonyms refer to abnormal heart sounds, such as murmurs, bruits, clicks, and rubs. These sounds are associated with heart disease, and their detection is important for diagnosis and management. In conclusion, heart sounds have several antonyms, reflecting different states of cardiac physiology and pathophysiology.