High-density lipoprotein (HDL) is commonly known as the "good" cholesterol, as it helps remove bad cholesterol from the body. However, there are also several synonyms for HDL that can be used interchangeably. These synonyms include alpha-lipoprotein, HDL-C, alpha-HDL, and alpha-cholesterol. The term "alpha" is often used to describe HDL because it reflects the fact that this lipoprotein molecule is the smallest and most dense of all the lipoproteins. In addition, HDL is referred to as "good" cholesterol because it plays a crucial role in fighting heart disease and promoting overall cardiovascular health. By using these synonyms, medical professionals can communicate more effectively about HDL and its benefits.