Hippel Lindau Disease, also known as VHL, is a rare hereditary condition characterized by the development of tumors in various parts of the body. Synonymous with VHL, this disease affects approximately 1 in 36,000 individuals globally. The condition is caused by a mutation in the VHL gene, which plays a crucial role in suppressing tumor growth. Its symptoms vary, encompassing renal cysts, tumors in the central nervous system, eyes, pancreas, and other areas. Synonyms for Hippel Lindau Disease include VHL Syndrome, von Hippel Lindau Syndrome, and VHL Disease. Early diagnosis and proper management are essential to minimize the potential complications associated with this condition.