Hirschsprung's Disease is a gastrointestinal disorder that is marked by the absence of ganglion cells in the lower part of the colon. It causes severe constipation and can lead to life-threatening complications if left untreated. Some of the synonyms of Hirschsprung's Disease include Congenital Megacolon, Aganglionic Megacolon, and Hirschsprung's Megacolon. Other terms used to describe the condition include Congenital Intestinal Aganglioniosis, Congenital Acquired Megacolon, and Congenital Aganglionic Intestinal Megacolon. While all these terms describe the same condition, they differ in their specific focus. However, they all point to the same disease that requires prompt medical attention to ensure effective treatment.