Homeotic mutation is a genetic abnormality that alters the development of an organism's body plan. Some synonyms for homeotic mutation include homeobox mutation, Hox gene mutation, developmental mutation, or morphological mutation. These mutations can cause significant changes in an organism's anatomy, such as the formation of an extra limb or the transformation of one body part into another. These mutations can occur spontaneously or as a result of exposure to environmental factors, such as radiation or certain chemicals. Studies on homeotic mutations have provided invaluable insights into the developmental processes of various organisms, including humans, and have contributed to the understanding of genetic disorders and diseases.