Hyperphosphorylation is a term used in biochemistry and cell biology to describe a process where a protein is excessively phosphorylated. This can lead to changes in the protein's function and structure and is often associated with disease states such as neurodegenerative disorders and cancer. Synonyms for hyperphosphorylation include over-phosphorylation, hyper-kinase activity, and phosphorylation overload. Other related terms include abnormal phosphorylation, uncontrolled phosphorylation, and pathological phosphorylation. Understanding the various terms and underlying mechanisms of hyperphosphorylation is essential for developing targeted therapies for diseases where this process plays a role in disease progression.