There are several synonyms for the phrase "in comfort." One possible synonym is "at ease," meaning a state of relaxation and ease. Another synonym could be "in luxury," implying a level of extravagance and indulgence. "Cozily" is another option, conveying a sense of warmth and snugness. "Comfortably" is a versatile synonym, encompassing both physical and emotional comfort. "Serene" implies a relaxed and peaceful state of mind. Finally, "contentedly" suggests a feeling of satisfaction and ease, often used to describe a person's demeanor or expression. Overall, these synonyms capture various aspects of the experience of being in comfort, from physical relaxation to emotional wellbeing.