If you're in need of alternative words for "in distress," don't fret. You can use "in agony" to describe a great deal of physical or emotional pain. If you're feeling overwhelmed or going through a tough time, you can use "in crisis" or "in trouble." "In dire straits" is an expression that suggests someone is in a terrible situation or under a lot of pressure. "In a bind" is a more informal way of describing a situation in which someone needs help. Alternatively, you can use "troubled" or "unhappy" to describe a situation or person who is feeling uneasy or upset. There are many helpful synonyms for "in distress," so choose the one that best describes the situation or person you're referring to.