When someone wants to express that something is absolutely not possible or cannot be done in any way, they could use several synonyms for the phrase "in no/not in any way, shape, or form." These include "by no means," "under no circumstances," "in no manner," and "not for all the tea in China." Another similar phrase would be "not in the least," which implies that there is no way something could happen, even in the smallest sense. Using any of these synonyms effectively conveys the speaker's certainty and emphasizes the importance of the statement being made.