In spite of appearance is a phrase that indicates that something is not as it seems on the surface. There are several synonyms for this phrase that can be used in different contexts. One of the most common synonyms for in spite of appearance is "despite the outward appearance." This phrase is often used to describe situations where something looks one way, but is actually something else entirely. Another synonym might be "contrary to expectation," which implies that something is surprising or unexpected. Other possible synonyms include "against all odds," "regardless of appearances," and "beneath the surface." These phrases all suggest that there is more to a situation than what meets the eye.