Inhibitory synapses are important in controlling the activity in neural circuits. These synapses release neurotransmitters that exert an inhibitory effect on the target neuron, reducing its excitability. There are several synonyms for the term inhibitory synapse including presynaptic inhibition, postsynaptic inhibition, or inhibitory neurotransmission. Presynaptic inhibition refers to the modulation of activity at the presynaptic terminal, while postsynaptic inhibition describes the suppression of activity at the postsynaptic membrane. Inhibitory neurotransmission refers to the process by which inhibitory signals are transmitted from one neuron to another across a synapse. Regardless of the terminology used, the role of inhibitory synapses in regulating neural activity is critical to maintaining proper brain function and behavior.