Insufflated refers to the process of blowing a substance, such as powder or medication, into a body cavity or passage using a device, such as an inhaler or insufflator. The antonym for insufflated would be to extract or remove a substance from a cavity or passageway. Some possible antonyms for insufflated include suctioned, extracted, drained, aspirated, or emptied. Depending on the context, other antonyms might include injected, swallowed, absorbed, or applied topically, as these would involve introducing a substance into the body in a different way than insufflation.