Insulin-like growth factor (IGF) is a protein hormone that plays a vital role in human growth and development. Synonyms for IGF include somatomedin, mechano growth factor (MGF), insulin-like growth factor-1 (IGF-1), and insulin-like growth factor-2 (IGF-2). IGF is produced by the liver and helps regulate cell growth and turnover, as well as muscle and bone growth. It also plays a critical role in regulating metabolism, glucose uptake, and energy storage. Several factors can affect IGF levels, including age, diet, exercise, and hormonal imbalances. IGF abnormalities can lead to various disorders, such as acromegaly, gigantism, or dwarfism. Understanding the different synonyms for IGF can assist in medical research and the diagnosis and treatment of these conditions.