The term inter-play implies a certain level of cooperation, connection or interactivity between two or more entities. If we were to seek for antonyms for this term, we would be looking for words that describe situations where such cooperation and interactivity are absent. Words like "isolation", "separation", "solitude" come to mind. In situations where inter-play is impossible, such as in the case of enemies or when dealing with isolated individuals, words like "confrontation", "antagonism", "discord" might be more fitting. However, regardless of the context, antonyms for inter-play typically describe situations where individuals or entities are not interacting or working together in a harmonious manner.