Intercalant is a chemical term that often appears in the fields of medicine, biology, and chemistry to describe a substance that can insert itself between the base pairs of DNA to manipulate its structure. Synonyms for intercalant include duplex-stabilizing agent or DNA-intercalating agent, which refer to the substance's ability to stabilize the twisted, double-helix structure of DNA. Other interchangeable terms for intercalants include planar or organic molecules, both of which describe the flat, non-polar structures that allow intercalants to fit snugly between the DNA base pairs. These terms are crucial in the development of new drugs and therapies that can target specific DNA structures and sequences to treat genetic diseases.