Interferome is a term used to describe the complete set of interferon stimulated genes (ISGs) that are activated by interferons. However, there are several synonyms that could be used to describe this term such as the interferon signal transduction pathway or the interferon-induced response. Other terms include the antiviral response, the innate immune response, and the interferon-responsive gene signature. These terms are often used interchangeably to describe the biological process that begins with the detection of a pathogen and leads to the activation of the immune response system. Ultimately, the use of synonyms for interferome highlights the complexity and importance of the body's ability to protect itself against various diseases and infections.