"Irremissibly" is a term used to describe something that cannot be forgiven, overlooked, or pardoned. Synonyms for "irremissibly" include "irreversibly," "irrevocably," "ineluctably," and "inescapably." These words all convey a sense of inevitability and finality, suggesting that there is no turning back once a certain action has been taken or a certain consequence has occurred. Other synonyms for "irremissibly" might include "unforgivably," "inexcusably," and "unpardonably," which emphasize the idea of moral culpability and the inability to escape blame or punishment for one's actions. Regardless of the specific term used, the message conveyed by "irremissibly" and its synonyms is one of grim finality and unavoidable consequences.