The phrase "is tight with" is often used to describe a close or intimate relationship between two people. However, there are many antonyms to this phrase, such as "distant from," "estranged from," "alienated from," "indifferent to," "cold towards," "aloof from," and "disengaged from." These antonyms show a lack of closeness, intimacy, or friendship between two people. They can be used to describe relationships that have become strained, distant, or disconnected. It is important to recognize these antonyms and use them appropriately in order to communicate effectively and accurately about the relationship between two people.