The term "Islets of Calleja" refers to a cluster of small, specialized neurons scattered throughout the brain, particularly in the ventral striatum. These minute structures are also known as "Calleja islands" or "Calleja neurons". "Islets of Calleja" play a crucial role in various brain functions, such as reward processing, motivation, and decision-making. Although tiny in size, their significance should not be undervalued. These "neural islets" act as integral parts of the brain's intricate network, contributing to overall cognitive and behavioral responses. So, the next time you come across "Islets of Calleja", remember that it simply refers to these important clusters of specialized neurons tucked away within the brain's circuitry.