Johne Disease, also known as paratuberculosis, is a chronic and debilitating condition that primarily affects ruminants such as cattle, sheep, and goats. This infectious disease is caused by the Mycobacterium avium subspecies Paratuberculosis (MAP). Although commonly referred to as Johne Disease, it is essential to be aware of its synonyms to prevent confusion and miscommunication. Some common synonyms for Johne Disease include paratuberculosis, paratuberculous enteritis, paraTB, and MAP infection. Recognizing these alternative names is crucial for effective communication among veterinarians, farmers, and researchers, ensuring accurate diagnosis, treatment, and prevention strategies are implemented to combat this economically significant disease.