The phrase "keeps one's shoulder wheel" means to persevere or persist despite difficulties or setbacks. There are numerous synonyms that capture this sense of determination, including "persevere," "persist," "endure," "continue," and "maintain." Other synonyms that convey a similar meaning include "perseverate," "press on," "stick to it," "hold fast," and "be resolute." Additionally, words like "dedication," "tenacity," "persistence," "determination," and "steadfastness" all capture the idea of not giving up in the face of obstacles. Whether you're facing personal challenges or working toward a specific goal, these synonyms can help you stay motivated and focused on achieving success.