"Lay waste to" is an idiom referring to the destruction or devastation of something. There are many synonyms for lay waste to, including demolish, devastate, ruin, wreck, ravage, obliterate, decimate, plunder, pillage, and desolate. These words all convey a sense of destruction or devastation, and can be used in a variety of contexts. For example, one might say that a tornado laid waste to a town, or that an army laid waste to a village during a battle. Regardless of the context, the use of these synonyms highlights the severity of the destruction, and can help to communicate the gravity of the situation to the reader or listener.