The phrase "laying up on" usually implies storing something or keeping it aside for later use. Antonyms for this phrase could include words that mean releasing, using or consuming something. For example, instead of "laying up on" food, one might choose to eat it immediately or share it with someone else. Similarly, instead of "laying up on" money, one might decide to invest it or spend it on necessary items. In terms of emotions, one could say they are "letting go of" or "releasing" negative feelings, rather than "laying up on" them. Ultimately, antonyms for "laying up on" involve action, as opposed to inaction or storing something away.