"Lays course" can be interpreted in multiple ways, thus, antonyms for this phrase could vary depending on its context. However, if interpreted as an idiom for charting a path or deciding a plan of action, the antonyms could be indecision, aimlessness, wanderlust, or spontaneity. On the other hand, if taken as the verb "lays" meaning to put or place down and "course" as a direction or route, the antonyms could be uproots, diverts, reroutes, or deviates. It is essential to know the precise meaning of the phrase before determining the antonyms.