Living in seclusion could also be referred to as living in isolation, withdrawal, solitude, or sequestration. Isolation refers to the state of being separated from others, whereas withdrawal is the act of retreating from social interactions. Solitude implies that someone has chosen to be alone, often for introspective or meditative purposes. Sequestration denotes being confined to a specific space or environment, often against one's will. Each of these synonyms carries distinct connotations, but they all share an element of being physically and socially distant from others. Whether by choice or circumstance, living in seclusion can have both positive and negative effects on a person's physical and mental health.