The term "loads up" refers to a person putting a lot of something into a particular space or container. The opposite of this term is "unloads," which means to remove something from a space or container. Additionally, other antonyms for "loads up" include "empties," "depletes," and "reduces." These terms imply a reduction in the amount of something being present in a space or container. Overall, while "loads up" suggests an increase, "unloads," "empties," "depletes," and "reduces" all involve a decrease in the amount of something present. Therefore, it is important to understand the context in which these words are used to effectively communicate a message.