Lobotomized refers to a process in which the frontal lobes of the brain are surgically removed or damaged, resulting in a significant change in behavior and personality. While this term is rarely used today due to the dangerous and outdated nature of the procedure, there are various synonyms that can be used to describe the same altered mental state. Words like mentally incapacitated, brain-damaged, or psychologically impaired are some common synonyms for lobotomized. These terms can be used to refer to individuals who have experienced brain trauma or have mental health conditions that affect their cognitive functioning and behavior.