Antonyms for "locks up" include releasing, freeing, opening, setting free, and letting go. When someone is released, they are allowed to leave a place where they were held. Freeing means that someone is no longer trapped or confined. If something is opened, it means that the object is no longer closed or sealed. Setting free represents that a person is released without any restrictions. Lastly, letting go refers to releasing or relinquishing something to allow for movement, growth, or progress. These antonyms represent the opposite of locking up because they all signify freedom from constraint or restriction.