The antonyms for "loses big" can be "wins big," "triumphs," "prevails," "succeeds," "gains," "profits," and "prospers." When someone wins a bet, gamble, game, or sport, they win big. Success can mean achieving one's goals or overcoming challenges. Profiting can mean gaining monetary or non-monetary advantages. Gaining can mean acquiring new knowledge, experience, or support. These antonyms signify a positive outcome, which is the opposite of losing big. By focusing on the antonyms of "loses big," individuals can alter their perspective and emphasize their successes and achievements, instead of dwelling on failures and setbacks.