Make larger is a frequently used phrase, and sometimes it's necessary to express its opposite or antonyms. The most appropriate antonyms for make larger are reduce, decrease, diminish, lower, and minimize. Reduce means to make something smaller or lessen its size or amount. Decrease is a synonym for reduce, and it also means to make something smaller or reduce its quantity. When we diminish something, we lessen its importance or value. Lower means to reduce or bring down, while minimize means to lessen the significance or impact of something. In short, the antonyms for make larger are words that describe the activity of reducing or making things smaller.