The antonyms for the term "making holy" refer to actions that move away from sanctity or holiness. Some of the antonyms include unscrupulous, unholy, irreverent, corrupt, sinful, impious, profane, and godless. These terms describe practices or values that contradict the idea of morality and purity. "Unholy" suggests being impure or contaminated, while "impiety" refers to irreverence towards religious beliefs. "Profane," on the other hand, describes something that is vulgar or blasphemous. Such words encompass the opposite of the values and beliefs promoted by the idea of making holy, and as such, they serve as useful antonyms for this term.