Manics is a colloquial term that refers to people who are hyperactive, overexcited or even insane. There are several synonyms that can be used instead of manics, such as lunatics, crazies, fanatics, zealots, and frenzied individuals. Lunatics are those who are mentally unstable, while crazies are those who behave in an irrational and unpredictable manner. Fanatics and zealots are individuals who are excessively passionate about a certain cause or belief. Lastly, frenzied individuals are those who are in a state of extreme excitement or agitation. These synonyms can be used interchangeably with manics depending on the context of the sentence.