Manuscript rejection is a difficult and discouraging part of the writing process, but it's important to remember that rejection does not define your writing abilities. Some useful synonyms for manuscript rejection include refusal, denial, dismissal, rebuff, turndown, and snub. It's understandable to feel disappointed when a manuscript is rejected, but it's important to keep in mind that rejection can be a springboard for growth. Use the feedback you receive from publishers or editors to improve your writing skills and to make your next manuscript even stronger. In the end, persistence and perseverance are the key factors to success in the writing industry.