Marie-Strumpell disease, also commonly known as ankylosing spondylitis, is a chronic rheumatic disorder that primarily affects the spine and sacroiliac joints. This condition eventually leads to stiffness and fusion of the affected joint resulting in chronic pain and limited mobility. While Marie-Strumpell disease is the most commonly used term to describe this condition, there are a few other synonyms that it might be referred to as. These include rheumatoid spondylitis, Bechterew's disease, and bamboo spine disease. Regardless of the term used, early diagnosis and management is crucial to prevent further deterioration of the spinal joints and to improve overall quality of life for those affected.