Antonyms for the word "matchup" are words that are opposite in meaning. The term matchup describes a situation where two teams or individuals compete against each other, and the antonyms for this term are words that convey other types of relations or lack of relationship. Antonyms for matchup could include words like divergence, dissimilarity, variance, variation, mismatch, or lack of similarity. A matchup is typically characterized by similarity, connection, or comparison, but antonyms for this term emphasize differences or a lack of connection. Therefore, using appropriate antonyms can help to convey a different meaning from the original word and add depth to your writing or communication.