"Minding one's p's and q's" is an idiom that means to be careful and avoid mistakes. Its antonyms would be carelessness, recklessness, disregard, and neglect. When someone is not minding their p's and q's, they are likely to make mistakes, overlook details, or behave in a sloppy manner. They might say or do something inappropriate without considering the consequences. In contrast, keeping track of one's p's and q's ensures that they stay focused, attentive, and responsible. It's an important trait to have in any situation that requires attention to detail, such as work, school, or personal relationships.