The mitotic checkpoint is a crucial process in the cell division cycle that ensures accurate allocation of genetic material between daughter cells. Synonyms for this term include spindle checkpoint, mitotic surveillance system, and mitotic spindle assembly checkpoint. The spindle checkpoint refers to the key role of the spindle apparatus in the process, while the mitotic surveillance system highlights the regulatory function of this process in monitoring errors during cell division. The term mitotic spindle assembly checkpoint emphasizes the importance of proper spindle formation for accurate chromosome segregation. Regardless of the terminology used, the mitotic checkpoint is a fundamental process in maintaining genomic stability and preventing cancerous growth.