Mixed transcortical aphasia is a disorder of language impairment that occurs due to damage to the brain's language centers. There are several synonyms for this condition, including global aphasia, total aphasia, and profound aphasia. The term global aphasia is used to describe the most severe form of the condition, where people are unable to produce or understand language in any form. Total aphasia is another term that refers to a similar condition where people experience complete loss of language abilities. In contrast, profound aphasia relates to a condition where individuals have profound difficulty speaking and comprehending language, but they can manage basic communication to some extent.