Most aggravated can be replaced with various synonyms in order to convey the same meaning. Some of the possible synonyms that can be used include incensed, irked, infuriated, exasperated, and annoyed. These words indicate a high level of irritation or annoyance. Other synonyms that may apply in specific contexts could include vexed, agitated, provoked, and irate. In general, the use of synonyms can help writers to add more variety and depth to their language, as well as to convey nuanced meanings that are specific to the context of their writing. By choosing the right synonym for "most aggravated," writers can help to create a more precise and evocative message.