Most amalgamated refers to something that is highly mixed or blended. The opposite of this word can be described as something that is isolated, separated, or distinct. Some possible antonyms for most amalgamated include segregated, uncombined, homogeneous, unmingled, or unmixed. These terms refer to objects or elements that are not blended or unified, but instead exist in separate components. For example, a segregated community is one that is separated by race, religion or class, whereas an unmingled mixture is composed of separate components that are not blended together. By knowing the antonyms for most amalgamated, we can better understand the context in which it is used and appreciate its meaning.