"Most chafed" means to be extremely irritated or annoyed. Antonyms for this phrase could be calm, placid, tranquil, unruffled, composed, or peaceful. Calm refers to being relaxed and free from disturbance. Placid denotes a state of serenity and peacefulness. Tranquil means to be calm and soothing. Unruffled depicts a state of composure and poise. Composed refers to being calm and in control of one's emotions. Finally, peaceful relates to a state of harmony and absence of conflict. These antonyms represent different states of mind and emotions that are in stark contrast to being "most chafed".