The antonyms for the word "most donothing" can vary depending on the context in which it is being used. If it is being referred to as a quality of a person, the antonyms can include active, busy, diligent, industrious, productive, energetic, and efficient. On the other hand, if it is being referred to as a situation or circumstance, the antonyms can be vibrant, lively, dynamic, active, bustling, and exciting. Thus, it is essential to consider the context in which the word "most donothing" is being used to determine the appropriate antonyms.