Most Eggheaded Antonyms: Simple, Unlearned, Ignorant, Unknowledgeable, Unschooled, Uninformed, Unstudied, Straightforward, Naive, Inexperienced, Unintellectual, Unread, Uninstructed, Illiterate, Unwise, Dull. These words are the opposite of most eggheaded. A person who is eggheaded is considered to have a lot of knowledge or is very knowledgeable on a specific subject, while a simple or ignorant person lacks knowledge or understanding. Someone who is eggheaded is usually regarded as intelligent and well-read. In contrast, someone who is unwise or naive may not have the same level of intellectualism or knowledge.