Ennui refers to a feeling of boredom or dissatisfaction. For the word "most ennuied," the opposite could be "most amused," which means to be entertained or delighted. Other antonyms could include "most engaged," which denotes involvement and interest, or "most stimulated," which refers to being mentally or physically excited. Another antonym could be "most interested," which is the opposite of being apathetic and uninterested. Overall, antonyms for "most ennuied" would encompass a range of emotions that are the opposite of boredom and disinterest, including excitement, engagement, and entertainment.