The phrase "most equanimous" implies a state of calmness and composure. Antonyms for this phrase could include discomposure, agitation, anxiety, turmoil, or unease. These words connote a lack of balance or steadiness, and are often associated with stress and emotional disturbance. They can describe feelings of being overwhelmed, panicked, or out of control. By contrast, equanimity suggests a state of tranquility and level-headedness, indicating a capacity to remain stable and centered in the face of challenging circumstances. When seeking to cultivate greater equanimity, it may be helpful to identify and work with the obstacles to this state of being.