The term "most gambled" can be substituted by several synonyms for specific contexts. "Most wagered" could be used in a more formal or business setting, while "most bet on" may be more appropriate for a casual conversation. "Most played" is a suitable alternative when referring to games of chance and luck, such as slot machines or roulette. In a sports betting context, "most favored" or "most popular pick" could be used instead. "Most risked" emphasizes the high stakes of gambling and is suitable for a more dramatic or cautionary context. Ultimately, the choice of synonym depends on the tone and audience of the communication.