What is another word for most headache?
Pronunciation: [mˈə͡ʊst hˈɛde͡ɪk] (IPA) 
When it comes to describing a situation or experience that causes a lot of frustration or stress, there are plenty of synonyms for the phrase "most headache." These include "major hassle," "huge annoyance," "big problem," "daunting challenge," "significant obstacle," "serious difficulty," "major setback," and "primary issue." Each of these phrases can be used to convey a similar sense of frustration and difficulty, but with slightly different nuances. Some may emphasize the magnitude or importance of the problem, while others may highlight the effort or complexity required to solve it. Whatever the situation, there are plenty of ways to express the idea of a challenging or frustrating experience.
