Antonyms for "most humorsome" could include "stern", "serious", "grave", "solemn", "dull", "unfunny", "unamusing", "unjoyful", or "unentertaining". These words denote a lack of humor or comedic effect, indicating a more serious or somber tone. Conversely, "most humorsome" implies a high level of amusement, levity, or lightheartedness. The choice of words to describe a situation, event, or individual can have a significant impact on how they are perceived. Therefore, it's wise to choose words that are precise, concise, and accurately reflect the intended meaning.