The word "most inspirited" implies a state of great motivation and enthusiasm. Its antonyms can include words like demoralized, discouraged, disheartened, and dejected. These antonyms describe a feeling of low energy, lack of enthusiasm or motivation, and can be caused by various factors such as failure, rejection, or disappointment. Other antonyms for "most inspirited" could include indifferent, apathetic, lethargic, and unenthusiastic, which suggest a complete absence of energy and motivation. Overall, using antonyms for "most inspirited" can help to emphasize the negative states of feeling that may be experienced by individuals who lack the motivation and inspiration needed to achieve their goals.