Most lithesome is commonly associated with agility, flexibility, and gracefulness. Therefore, antonyms for this term would include words that imply being clumsy, rigid, and inflexible. Some antonyms for "most lithesome" could be awkward, clumsy or cumbersome. Alternatively, some suitable antonyms, such as ungraceful, uncoordinated, ungainly, or unwieldy, would be appropriate. Additionally, the antonyms weak and lethargic could also apply, as both suggest a lack of dynamism and energy. It is essential to note that antonyms of most lithesome may vary, depending on the context in which they are used. In conclusion, most lithesome may have plenty of antonyms depending on the context of the sentence.